Volume 26, Issue 1, 2026 January - March
| Volume 26, No 1 | Pages: |
| 2026 January - March | Articles: 0 |
Sighting report of critically endangered Baer’s Pochard Athya baeri (Radde, 1863) from Champhai, Mizoram, India
Lawmsangzuala Chhangte, Rochamliana, Lalnunthara, RE Remruata, C Vanlalrema, Zakhuma Don, Lalnunsiama, Lalnuntluanga, HT Hnamtinkhuma, PC Lalramtiama, Thangkima Renthlei, Zarzoliana, C. Lallawmkima, Ramsiamliana, Vohbika Don, Vanlalhruaizela, Laldingzela Ralte, Lalawmawia Sailo
In this paper we report the first confirmed sighting of Baer’s Pochard Aythya baeri (Radde, 1863) from Mizoram. Baer’s Pochard belongs to the family Anatidae and is reported from Bangladesh, Bhutan, India, Japan, China, Mongolia, Hongkong, South Korea, North Korea, Laos, Myanmar, Russia, Pakistan, Phillipines, Thailand and Vietnam. In Mizoram, this is the only sighting report and photographic record for this species; details of sightings and habitat are discussed.
Comprehensive overview of BRCA1 in breast cancer: molecular mechanisms, multi-omics approaches, and therapeutic strategies
Priyanka Namdev, Vignesh Krishnasamy, Ashok K. Varma, Nachimuthu Senthil Kumar
BRCA1 is a tumor suppressor gene which is involved in repair of DNA, regulation of cell cycle, support of genome stability and other crucial physiological highlights. Numerous hereditary and natural variables are included in breast cancer advancement over different social orders. Among all of these factors in families with a history of breast cancer all through a few periods, hereditary genes, like inclining qualities to create this malady, ought to be considered more, since transformations within the BRCA1 and BRCA2 essentially increment the chance of breast and other cancer. Early discovery of transformation carriers in these genes, in turn, can play a vital part in its avoidance. Additionally, treatment approaches for BRCA1-associated breast tumors have demonstrated encouraging success, including PARP inhibitors, platinum-based chemotherapy, and newly developed targeted treatments. This review, summarize the molecular roles of BRCA1, its connection to the pathophysiology of breast cancer, existing therapeutic approaches, and recent multi-omics findings. It is anticipated that a more thorough integration of multi-omics data will enhance clinical outcomes and personalized treatment for patients with BRCA1 mutated breast cancer.
Luminescence properties of Tb3+, Eu3+ ions doped silicon dioxide
Europium (Eu3+) and Terbium (Tb3+) singly doped and double doped with Silicon dioxide (SiO2) is synthesized successfully by the sol-gel process. A xenon lamp light source with wavelength, λe= 370 nm is used for exciting the sample. The excitation spectra of Eu3+ ion may show applications in the area of UVB, near UVA and green light regions. Magnetic-dipole transition (5D0→7F1) is the dominant transition in emission spectra of Eu3+ ion. The emission spectra of Tb3+ ion reveal four strong emission peaks at 488nm, 545nm, 586nm and 623nm due to the transitions of 5D4→7F6, 5D4→7F5, 5D4→7F4 and 5D4→7F3 respectively with the transition 5D4→7F5 (green emission) as the most intense. The excitation of their co-doped spectra also evident that there is transfer of energy from Tb3+ ion to Eu3+ ion in silicon dioxide.
In vitro and in vivo antioxidant activities of the hydro-alcoholic extract of Stemona tuberosa Lour
C. Malsawmtluangi , H. Lalhlenmawia and Mevareen Rynjah
The study was undertaken to evaluate the in vitro and in vivo antioxidant activities of a traditionally used medicinal plant, Stemona tuberosa. The roots of the S. tuberosa were processed for chemical extraction with a hydro-alcoholic solution. Phytochemical screening was done to evaluate the secondary metabolite constituents. In vitro antioxidant activity was assessed by different methods such as 2,2-diphenyl-1-picrylhydrazyl (DPPH) scavenging activity, hydroxyl radical scavenging method and reducing power capacity. The total phenolic content and total flavonoid content were also determined. In vivo antioxidant activity was performed on 36 male rats, randomly divided into six groups, and then treated with different antioxidant drugs and the plant extract. Oxidative stress was induced in Group 2 to Group 6 animals with streptozotocin (STZ). On the 15th day, the animals were sacrificed, and biochemical analysis was done to estimate the antioxidant parameters. The hydro-alcoholic extracts of the plant contained alkaloids, carbohydrates, proteins and amino acids, steroids, triterpenoids, phenols, tannins, flavonoids, glycosides, saponins and volatile oils. Antioxidant activity was exhibited by the plant extract with the IC50 of 0.048 mg/ml and 0.051 mg/ml in DPPH and hydroxyl radical scavenging activity respectively. The reducing power of the extract showed concentration-dependent antioxidant reaction. The total phenolic compounds detected in the plant extract was 170.85 mg/g dry weight expressed as gallic acid equivalent (GAE) and flavonoids content was 83.3 mg quercetin equivalent (QE)/g dry weight. In in vivo study, the extract showed a significant increase (p<0.05) in Superoxide dismutase (SOD) and reduced Glutathione (GSH) level while there is a significant decrease (P<0.05) in Malondialdehyde (MDA) level. This study suggests that the hydro-alcoholic extract of S. tuberosa exhibited antioxidant activity. In vitro tests indicated a good antioxidant reaction and the presence of strong antioxidant compounds. In vivo experiments further revealed powerful antioxidant enzyme functions. Thus, the usefulness of the plant as a medicinal plant is supported.
Magnetostratigraphic study of the Bhuban Formation (Surma Group) in Midum Kham, Aizawl, Mizoram
Lalengzuali , Paul Lalnuntluanga, J Malsawma, C Lalremruatfela, Lalhruaitluanga, Lalremruata, Dennis Lalhruaitluanga, Orizen MS Dawngliana, Lalramengi Fanai, Arman Boruah
Magnetostratigraphic analysis was conducted on a ~380 m thick succession of the upper Bhuban Formation (Surma Group) exposed between Thiak and Sumsuih villages in Aizawl District, Mizoram. The study section yielded three normal and two reverse magnetozones, with GPTS-correlated ages ranging from ~9.308 Ma at the base to ~8.699 Ma at the top, spanning a total duration of ~0.609 Ma. The average sediment accumulation rate (SAR) is approximately 24.305 cm/ka, the lower part of the section exhibits a peak of 46.8 cm/ka prior to ~9.65 Ma. The subsequent decline in SAR to 11.02 cm/ka at approximately 9.45 Ma suggests a potential hiatus in the upper part of the succession that warrants further investigation.
Palaeo-environmental reconstruction of the Bhuban rocks of the Bhuban Formation, Surma Group exposed in the Midum Kham: an insight from ichnology
Lalengzuali, Lalramengi Fanai , A. Lalrammuana, Lalhruaitluanga, Lalremruata, Dennis Lalhruaitluanga, Orizen MS Dawngliana, J. Malsawma, Paul Lalnuntluanga
The Bhuban rocks exposed in Midum Kham, Aizawl District of Mizoram, contains a rich ichnofossil assemblage. The present study aimed at establishing the palaeo environmental conditions of the sedimentary rocks of the study area. The trace fossils recorded comprise 14 ichnospecies of 9 ichnogenera have been identified which include Arenicolites carbonarius, Cochlichnus anguineus, Diplocraterion parallelum, Ophiomorpha nodosa, Palaeophycus tubularis, P. striatus, Planolites isp., Skolithos linearis, Skolithos verticals, Skolithosisp., Teichichnus rectus, Thalassinoides horizontalis, T. suevicus and T. paradoxicus. Ethologically these ichnogenera display dwelling and feeding activities of the infaunal organisms. Arenicolites, Ophiomorpha, Diplocraterion, Skolithos are the members of the Skolithos ichnofacies while Palaeophycus, Planolites and Thalassinoides are the members of the Cruziana ichnofacies. These ichnofacies indicate an upper shoreface to offshore transition shallow marine palaeoenvironment with fluctuating energy conditions during the deposition of the rocks of the Bhuban Formation of Mizoram.
(CC BY 4.0) 2026 Mizo Academy of Sciences. Online since 31 March 2009
ISSN 0975-6175 (print)/2229-6026 (online)
Crafted with care by
Lailen Consulting